Cold-induced thermogenesis in humans

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Brown adipose tissue is involved in the seasonal variation of cold-induced thermogenesis in humans.

Brown adipose tissue (BAT) contributes to whole-body energy expenditure (EE), especially cold-induced thermogenesis (CIT), in humans. Although it is known that EE and CIT vary seasonally, their relationship with BAT has not been investigated. In the present study, we examined the impact of BAT on seasonal variations of EE/CIT and thermal responses to cold exposure in a randomized crossover desi...

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Cold-induced thermogenesis in rats nutritionally deprived early in life.

Preweaning nutritional deprivation with or without postweaning partial energy restriction produces animals of small size with defective nonshivering thermogenesis. This is also associated with their inability to tolerate cold exposure to 5 degrees C. Adequate nutritional rehabilitation for a reasonable length of time of 10 days abolishes the defect in cold induced thermogenesis (CIT) although t...

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Cold tolerance, cold-induced hyperphagia, and nonshivering thermogenesis are normal in 1-AMPK / mice

Jake D. Bauwens, Eric G. Schmuck, Christopher R. Lindholm, Rebecca L. Ertel, Jacob D. Mulligan, Ian Hovis, Benoit Viollet, and Kurt W. Saupe Departments of Medicine and Physiology, University of Wisconsin, Madison, Wisconsin; and Institut Cochin, Université Paris Descartes, Centre National de la Recherche Scientifique UMR8104, Institut National de la Santé et de la Recherche Médicale U1016, Par...

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Cold tolerance, cold-induced hyperphagia, and nonshivering thermogenesis are normal in α₁-AMPK-/- mice.

Recent studies indicate that a substantial amount of metabolically active brown adipose tissue (BAT) exists in adult humans. Given the unique ability of BAT to convert calories to heat, there is intense interest in understanding the regulation of BAT metabolism in hopes that its manipulation might be an effective way of expending excess calories. Because of the established role of AMP-activated...

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Increased systolic blood pressure after mild cold and rewarming: relation to cold-induced thermogenesis and age.

AIM Higher winter mortality in elderly has been associated with augmented systolic blood pressure (SBP) response and with impaired defense of core temperature. Here we investigated whether the augmented SBP upon mild cold exposure remains after a rewarming period, and whether SBP changes are linked to thermoregulation. Therefore, we tested the following hypotheses: cold-induced increase in SBP ...

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ژورنال

عنوان ژورنال: European Journal of Clinical Nutrition

سال: 2016

ISSN: 0954-3007,1476-5640

DOI: 10.1038/ejcn.2016.223